SOD3 Antibody
SOD3 is a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. This protein is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P08294
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 7-36 from the human protein was used as the immunogen for this SOD3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SOD3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SOD3 antibody is available for research use only.
Storage Conditions
Aliquot the SOD3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SOD3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasm, extracellular matrix
Image Legend
Western blot analysis of SOD3 antibody and K562 lysate. Predicted molecular weight: 26~32 kDa.
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