CEBPB Antibody

CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, Flow Cytometry: 1:10-1:50

UniProt

P17676

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 271-298 from the human protein was used as the immunogen for this CEBPB antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC, FACS, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CEBPB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CEBPB antibody is available for research use only.

Storage Conditions

Aliquot the CEBPB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the CEBPB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Rat, Bovine, Chicken

Image Legend

Western blot analysis of CEBPB antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the CEBPB gene (2) . Expected molecular weight: 36-41 kDa.