PINK1 Antibody
Defects in PINK1 are the cause of autosomal recessive early-onset Parkinson's disease 6 (PARK6) . Six novel pathogenic PINK1 mutations suggest that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. Strong evidence indicates that, although important in mendelian forms of Parkinson's disease (PD), PINK1 does not influence the cause of sporadic nonmendelian forms of PD.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
Q9BXM7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 118-147 from the human protein was used as the immunogen for this PINK1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Store at 4oC for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PINK1 antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the PINK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot analysis of lysate from human placenta tissue, using Park6/ PINK1 antibody diluted at 1:1000. Predicted molecular weight: 60-70 kDa
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