Parkin Antibody / PARK2
Parkinson is the second most common neurodegenerative disease after Alzheimers. About 1 percent of people over the age of 65 and 3 percent of people over the age of 75 are affected by the disease. The mutation is the most common cause of Parkinson disease identified to date. The function of Park2 is not well-known; however, it may play a role in the ubiquitin-mediated proteolytic pathway. Mutations in this gene are known to cause autosomal recessive juvenile parkinsonism. Alternative splicing of this gene produces three known products of undetermined function.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:250-1:1000, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50, IHC (Paraffin) : 1:10-1:50
UniProt
O60260
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 111-140 from the human protein was used as the immunogen for this Parkin antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, IHC, WB, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Parkin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Parkin antibody is available for research use only.
Storage Conditions
Aliquot the Parkin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Parkin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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