PARP Antibody
PARP is a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
Product Specifications
CAS Number
9007-83-4
UniProt
P09874
Host
Rabbit
Immunogen
A portion of amino acids 183-214 from the human protein was used as the immunogen for this PARP antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PARP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PARP antibody is available for research use only.
Documents
Frequently Asked Questions
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