IL1R1 Antibody
IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9) . Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P14778
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 474-503 from human IL-1 Receptor type 1 was used as the immunogen for this IL1R1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IL1R1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IL1R1 antibody is available for research use only.
Storage Conditions
Aliquot the IL1R1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IL1R1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Rat
Image Legend
Western blot analysis of IL1R1 antibody and HL-60 lysate. Predicted molecular weight 60-65 kDa.
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