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Amyloid beta Antibody

APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Aβ is the main component of amyloid plaques (extracellular deposits found in the brains of patients with Alzheimer's disease) .[19] Similar plaques appear in some variants of Lewy body dementia and in inclusion body myositis (a muscle disease), while Aβ can also form the aggregates that coat cerebral blood vessels in cerebral amyloid angiopathy. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P05067

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 736-770 from the human protein was used as the immunogen for this Amyloid beta antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Amyloid beta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Amyloid beta antibody is available for research use only.

Storage Conditions

Aliquot the Amyloid beta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Amyloid beta antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Pig, Rat

Image Legend

Western blot analysis of Amyloid beta antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the APP gene (2) . Predicted molecular weight 79~120kDa depending on glycosylation level.

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