SIRT6 Antibody
SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Product Specifications
CAS Number
9007-83-4
Specifications
IHC (Paraffin) : 1:50-1:100, Western blot: 1:1000
UniProt
Q8N6T7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 290-319 from the human protein was used as the immunogen for this SIRT6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the SIRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SIRT6 antibody is available for research use only.
Storage Conditions
Aliquot the SIRT6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the SIRT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of SIRT6 antibody and mouse stomach tissue lysate
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