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XIAP Antibody

BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100

UniProt

P98170

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this XIAP antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the XIAP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This XIAP antibody is available for research use only.

Storage Conditions

Aliquot the XIAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the XIAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of XIAP antibody and Ramos lysate. Expected/observed molecular weight ~57 kDa.

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