Angiotensin-converting enzyme 2 Antibody
ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, ELISA: peptide immunogen
UniProt
Q9BYF1
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 773-805 from the human protein was used as the immunogen for this Angiotensin-converting enzyme 2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Angiotensin-converting enzyme 2 antibody is available for research use only.
Storage Conditions
Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Angiotensin-converting enzyme 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of the Angiotensin-converting enzyme 2 antibody in K562 lysate. Predicted molecular weight: 90-100 kDa.
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