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Angiotensin-converting enzyme 2 Antibody

ACE2 is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE converts angiotensin I to angiotensin II, ACE2 converts angiotensin I to angiotensin 1-9, which has 9 amino acids. Angiotensin II is a potent blood vessel constrictor, while angiotensin 1-9 does not impact blood vessels but is cleaved by ACE to a shorter peptide, angiotensin 1-7, which is a blood vessel dilator.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, ELISA: peptide immunogen

UniProt

Q9BYF1

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 773-805 from the human protein was used as the immunogen for this Angiotensin-converting enzyme 2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Angiotensin-converting enzyme 2 antibody is available for research use only.

Storage Conditions

Aliquot the Angiotensin-converting enzyme 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Angiotensin-converting enzyme 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of the Angiotensin-converting enzyme 2 antibody in K562 lysate. Predicted molecular weight: 90-100 kDa.

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