CD63 Antibody / LAMP-3
CD63 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. The use of alternate polyadenylation sites has been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (FFPE) : 1:25, FACS: 1:25 per 1x10^6 cells
UniProt
P08962
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 163-190 from the human protein was used as the immunogen for this CD63 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, FACS
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CD63 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CD63 antibody is available for research use only.
Storage Conditions
Aliquot the CD63 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CD63 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasm, cell surface and secreted
Image Legend
Frequently Asked Questions
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