XRCC6 Antibody
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50
UniProt
P12956
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 228-254 from the human protein was used as the immunogen for this XRCC6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, FACS, IF, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the XRCC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This XRCC6 antibody is available for research use only.
Storage Conditions
Aliquot the XRCC6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the XRCC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
XRCC6 antibody western blot analysis in 1) 293 and 2) A549 lysate
Documents
Frequently Asked Questions
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