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XRCC6 Antibody

XRCC6 is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100, Flow Cytometry: 1:10-1:50, Immunofluorescence: 1:10-1:50

UniProt

P12956

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 521-548 from the human protein was used as the immunogen for this XRCC6 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, FACS, IF, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the XRCC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This XRCC6 antibody is available for research use only.

Storage Conditions

Aliquot the XRCC6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the XRCC6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of XRCC6 antibody and A2058 lysate.

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