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CCR7 Antibody

CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50

UniProt

P32248

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 11-37 from the human protein was used as the immunogen for this CCR7 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, IF, FACS, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CCR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CCR7 antibody is available for research use only.

Storage Conditions

Aliquot the CCR7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the CCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

CCR7 antibody western blot analysis in 293 (lane 1), Ramos (2), MDA-MB231 (3) cell line and mouse spleen tissue (4) lysate. Predicted size ~45 kDa

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