CCR7 Antibody
CCR7 is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Immunofluorescence: 1:10-1:50, Flow Cytometry: 1:10-1:50
UniProt
P32248
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 11-37 from the human protein was used as the immunogen for this CCR7 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, IF, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CCR7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CCR7 antibody is available for research use only.
Storage Conditions
Aliquot the CCR7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CCR7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
CCR7 antibody western blot analysis in 293 (lane 1), Ramos (2), MDA-MB231 (3) cell line and mouse spleen tissue (4) lysate. Predicted size ~45 kDa
Documents
Frequently Asked Questions
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