Phospho-KDR Antibody / VEGFR2 (pY1175)
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..
Product Specifications
CAS Number
9007-83-4
Specifications
Dot blot: 1:500
UniProt
P35968
Host
Rabbit
Reactivity
Human
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
DB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho-KDR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho-KDR antibody is available for research use only.
Storage Conditions
Aliquot the phospho-KDR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the phospho-KDR antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Location
Cytoplasmic and cell surface
Image Legend
Dot blot analysis of phospho-KDR antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Frequently Asked Questions
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