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Phospho-NFATC2 Antibody (pS330)

NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. It is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response.

Product Specifications

CAS Number

9007-83-4

Specifications

Dot blot: 1:500

UniProt

Q13469

Host

Rabbit

Reactivity

Human

Immunogen

This phospho-NFATC2 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS330 of human NFATC2.

Clonality

Polyclonal

Isotype

Ig

Applications

DB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the phospho-NFATC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This phospho-NFATC2 antibody is available for research use only.

Storage Conditions

Aliquot the phospho-NFATC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the phospho-NFATC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Dot blot analysis of phospho-NFATC2 antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

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