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Phospho-BRAF Antibody (pS445)

BRAF is involved in the transduction of mitogenic signals from the cell membrane to the nucleus. It may play a role in the postsynaptic responses of hippocampal neuron. Defects in BRAF are a cause of cardiofaciocutaneous syndrome (CFC syndrome), and a wide range of cancers such as lung cancer, non-Hodgkins lymphoma, and colorectal cancer.

Product Specifications

UniProt

P15056

Host

Rabbit

Immunogen

This phospho-BRAF antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS445 of human BRAF.

Clonality

Polyclonal

Isotype

Ig

Applications

DB, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the phospho-BRAF antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This phospho-BRAF antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6681000/datasheet/f48514-0.4ml.pdf

CAS Number

9007-83-4

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