Phospho c-Myc Antibody (pT58)
c-Myc participates in the regulation of gene transcription. It binds DNA both in a non-specific manner and also specifically to recognizes the core sequence 5'-CAC[GA]TG-3'. This protein appears to activate the transcription of growth-related genes. Overexpression of MYC is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC may be a cause of a form of B-cell chronic lymphocytic leukemia.
Product Specifications
CAS Number
9007-83-4
UniProt
P01106
Host
Rabbit
Immunogen
Clonality
Polyclonal
Isotype
Ig
Applications
DB, WB, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the phospho c-Myc antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This phospho c-Myc antibody is available for research use only.
Documents
Frequently Asked Questions
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