P70 S6 Kinase Antibody
RPS6KB1 is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding the gene for RPS6KB1 and overexpression of this kinase are seen in some breast cancer cell lines.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P23443
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 405-434 from the human protein was used as the immunogen for this p70 S6 Kinase antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the p70 S6 Kinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This p70 S6 Kinase antibody is available for research use only.
Storage Conditions
Aliquot the p70 S6 Kinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the p70 S6 Kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Bovine, Mouse, Rabbit, Rat
Image Legend
Frequently Asked Questions
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