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Phospho-TrkA Antibody (pY791)

TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Product Specifications

CAS Number

9007-83-4

Specifications

Dot blot: 1:500, Western blot: 1:500-1:1000

UniProt

P04629

Host

Rabbit

Reactivity

Human

Immunogen

This phospho-TrkA antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY791 of human TrkA.

Clonality

Polyclonal

Isotype

Ig

Applications

DB, WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the phospho-TrkA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This phospho-TrkA antibody is available for research use only.

Storage Conditions

Aliquot the phospho-TrkA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.nsjbio.com/tds-pdf/phospho-trka-antibody-py791-f48462

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the phospho-TrkA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Dot blot analysis of phospho-TrkA antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.

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