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CD105 Antibody

CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.

Product Specifications

UniProt

P17813

Host

Rabbit

Immunogen

A portion of amino acids 380-409 from the human protein was used as the immunogen for this CD105 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, FACS, ELISA

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CD105 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD105 antibody is available for research use only.

Product Datasheet

https://cdn.gentaur.com/products/800/6680886/datasheet/f48291-0.4ml.pdf

CAS Number

9007-83-4

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