β-Glucuronidase-IN-2

Product Specifications

UNSPSC Description

β-Glucuronidase-IN-2 is a potent E. coli β-glucuronidase inhibitor with an IC50 value of 0.24 μM, an Ki value of 1.09 μM. β-Glucuronidase-IN-2 shows antiproliferative activity. β-Glucuronidase-IN-2 has the potential for the research of anti-cancer and anti-inflammatory therapies[1].

Target Antigen

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/β-glucuronidase-in-2.html

Solubility

10 mM in DMSO

Smiles

OC1=C(C=C(C=C1Cl)O)CC2=C[C@H](O)[C@@H](O)[C@@]3(CCC4=C(O3)C(Cl)=C(Cl)C(O)=C4)C2=O

Molecular Weight

487.71

References & Citations

[1]YichaoGe, et al. Exploring gabosine and chlorogentisyl alcohol derivatives from a marine-derived fungus as EcGUS inhibitors with informatic assisted approaches. European Journal of Medicinal Chemistry, 2022, 114699.