IRF8 Antibody
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
Q02556
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 241-269 from the human protein was used as the immunogen for this IRF8 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the IRF8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This IRF8 antibody is available for research use only.
Storage Conditions
Aliquot the IRF8 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of IRF8 antibody and Jurkat lysate. Predicted molecular weight ~48kDa.
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