TRF1 Antibody
TERF1/TRF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P54274
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 337-366 from the human protein was used as the immunogen for this TRF1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TRF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TRF1 antibody is available for research use only.
Storage Conditions
Aliquot the TRF1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TRF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Hamster
Image Legend
Western blot analysis of TRF1 antibody and Jurkat lysate. Predicted molecular weight: ~50kDa.
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