KLF4 Antibody
Kruppel-like factor 4 (KLF4) is a transcription factor involved in both proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas and has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. KLF4 is also involved in reprogramming differentiated cells into pluripotent stem cells. KLF4 can act as a transcriptional activator or repressor, but the underlying mechanisms are poorly understood.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O43474
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 20-53 from the human protein was used as the immunogen for this KLF4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the KLF4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This KLF4 antibody is available for research use only.
Storage Conditions
Aliquot the KLF4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the KLF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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