PHB Antibody / Prohibitin

Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P35232

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 182-211 from the human protein was used as the immunogen for this PHB antibody.

Clonality

Polyclonal

Isotype

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PHB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PHB antibody is available for research use only.

Storage Conditions

Aliquot the PHB antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the PHB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Mouse, Rat, Bovine

Image Legend

Western blot analysis of PHB antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the PHB1 gene (2) . Predicted molecular weight ~29 kDa.