CPT1A Antibody / CPT1-L
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
P50416
Host
Rabbit
Reactivity
Human, Bovine
Immunogen
A portion of amino acids 606-636 from the human protein was used as the immunogen for this CPT1A antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, WB, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CPT1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CPT1A antibody is available for research use only.
Storage Conditions
Aliquot the CPT1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the CPT1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of CPT1A antibody and Y79 lysate. Predicted molecular weight ~86kDa.
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