CHK1 Antibody
Checkpoint kinase 1, commonly referred to as CHK1 is an serine/threonine-specific protein kinase that in humans, is encoded by the CHEK1 gene. CHK1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O14757
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 258-287 from the human protein was used as the immunogen for this CHK1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Store at 4oC for up to one month. For long term, aliquot the CHK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CHK1 antibody is available for research use only.
Storage Conditions
Store at 4°C for up to one month. For long term, aliquot the CHK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Chk1 antibody western blot analysis in (1) HeLa cell line and (2) mouse thymus tissue lysate. Predicted molecular weight ~54kDa.
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