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Myostatin Antibody / GDF8

GDF8/Myostatin is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:50

UniProt

O14793

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 9-38 from the human protein was used as the immunogen for this Myostatin antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC, WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Myostatin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Myostatin antibody is available for research use only.

Storage Conditions

Aliquot the Myostatin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Myostatin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine, Pig

Image Legend

IHC analysis of FFPE human skeletal muscle tissue stained with Myostatin antibody

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