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VEGF-C Antibody

VEGFC is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50, Flow Cytometry: 1:10-1:50

UniProt

P49767

Host

Rabbit

Reactivity

Human

Immunogen

This VEGF-C antibody was produced from rabbits immunized with human recombinant protein.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, FACS, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the VEGF-C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This VEGF-C antibody is available for research use only.

Storage Conditions

Aliquot the VEGF-C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the VEGF-C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of VEGF-C antibody and 293 lysate. Predicted molecular weight ~45 kDa.

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