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VEGFC Antibody

VEGFC is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50

UniProt

P49767

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 248-277 from the human protein was used as the immunogen for this VEGFC antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the VEGFC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This VEGFC antibody is available for research use only.

Storage Conditions

Aliquot the VEGFC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the VEGFC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC analysis of FFPE human lung carcinoma tissue stained with VEGFC antibody

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