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SMAD6 Antibody

The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

O43541

Host

Rabbit

Reactivity

Mouse

Immunogen

A portion of amino acids 357-386 from the human protein was used as the immunogen for this SMAD6 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the SMAD6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SMAD6 antibody is available for research use only.

Storage Conditions

Aliquot the SMAD6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the SMAD6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

SMAD6 antibody western blot analysis in mouse Neuro-2a lysate. Observed molecular weight: 50~60 kDa.

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