TSC2 Antibody
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product Specifications
CAS Number
9007-83-4
Specifications
IHC (Paraffin) : 1:25, Western blot: 1:1000
UniProt
P49815
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1397-1426 from the human protein was used as the immunogen for this TSC2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC, WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TSC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TSC2 antibody is available for research use only.
Storage Conditions
Aliquot the TSC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TSC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
TSC2 antibody western blot analysis in 293 lysate. Predicted molecular weight ~200 kDa.
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