BMPR1A Antibody

On ligand binding, BMPR1A forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction (By similarity) . [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, Flow Cytometry: 1:10-1:50

UniProt

P36894

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1-30 from the human protein was used as the immunogen for this BMPR1A antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, WB, ELISA

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the BMPR1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This BMPR1A antibody is available for research use only.

Storage Conditions

Aliquot the BMPR1A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the BMPR1A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of lysate from 1) HeLa, 2) K562, 3) MCF-7 cell line, 4) human liver and 5) mouse liver tissue lysate using BMPR1A antibody at 1:1000. Predicted molecular weight ~60 kDa.