ASCL1 Antibody / MASH1
This gene encodes 'Achaete scute complex homolog like 1' (ASCL1) or 'Mammalian achaete scute complex homolog 1' (MASH1), a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3') . Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P50553
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 63-90 from the human protein was used as the immunogen for this MASH1 / ASCL1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ASCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ASCL1 antibody is available for research use only.
Storage Conditions
Aliquot the ASCL1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the ASCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
ASCL1 antibody western blot analysis in NCI-H460 lysate. Observed molecular weight ~34 kDa.
Frequently Asked Questions
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