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CXCR4 Antibody

This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

Product Specifications

CAS Number

9007-83-4

UniProt

P61073

Host

Rabbit

Immunogen

A portion of amino acids 50-79 from the human protein was used as the immunogen for this anti-CXCR4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the anti-CXCR4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This anti-CXCR4 antibody is available for research use only.

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