Nkx3.1 Antibody
Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity) . Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands) . Essential for appropriate differentiation and secretory function of the bulbourethral gland.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P97436
Host
Rabbit
Reactivity
Mouse
Immunogen
A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Nkx3.1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Nkx3.1 antibody is available for research use only.
Storage Conditions
Aliquot the Nkx3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the Nkx3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Nkx3.1 antibody western blot analysis in mouse stomach tissue lysate. Predicted molecular weight ~28 kDa, observed at 28-38 kDa.
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