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Nkx3.1 Antibody

Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor (By similarity) . Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Act as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to suppress growth and tumorigenicity of prostate carcinoma cells. Play a role in the formation of minor salivary glands (particularly palatine and lingual glands) . Essential for appropriate differentiation and secretory function of the bulbourethral gland.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P97436

Host

Rabbit

Reactivity

Mouse

Immunogen

A portion of amino acids 3-1 from the mouse protein was used as the immunogen for this Nkx3.1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Nkx3.1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Nkx3.1 antibody is available for research use only.

Storage Conditions

Aliquot the Nkx3.1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the Nkx3.1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Nkx3.1 antibody western blot analysis in mouse stomach tissue lysate. Predicted molecular weight ~28 kDa, observed at 28-38 kDa.

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