LAMP1 Antibody / CD107A

The LAMP1 glycoprotein is a type I transmembrane protein which is expressed at high or medium levels in at least 76 different normal tissue cell types. It resides primarily across lysosomal membranes, and functions to provide selectins with carbohydrate ligands. It has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells and may also play a role in tumor cell differentiation and metastasis. [Wiki]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000, IHC (Paraffin) : 1:10-1:50

UniProt

P11279

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 125-154 from the human protein was used as the immunogen for this LAMP1 antibody.

Clonality

Polyclonal

Isotype

Applications

IHC, WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS pH 7.4 with 0.09% sodium azide

Reconstitution

Aliquot the LAMP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This LAMP1 antibody is available for research use only.

Storage Conditions

Aliquot the LAMP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the LAMP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot analysis of lysate from HeLa, HT1080 and human placenta lysate (left to right), using LAMP1 antibody at 1:1000. This heavily glycosylated protein of 417 amino acids is visualized at up to ~140 kDa.