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SIRT4 Antibody

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

Q9Y6E7

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 67-95 from the human protein was used as the immunogen for this SIRT4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the SIRT4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SIRT4 antibody is available for research use only.

Storage Conditions

Aliquot the SIRT4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the SIRT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Prediction Reactivity

Bovine

Image Legend

SIRT4 antibody western blot analysis in mouse testis tissue lysate.

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