E-Selectin Antibody
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P16581
Host
Rabbit
Reactivity
Human
Immunogen
This E-Selectin antibody was produced from rabbits immunized with a human partial recombinant protein.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the E-Selectin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This E-Selectin antibody is available for research use only.
Storage Conditions
Aliquot the E-Selectin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the E-Selectin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
E-Selectin antibody western blot analysis in NCI-H460 lysate. Predicted molecular weight: 64-115 kDa depending on glycosylation level.
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