LC3B Antibody (MAP1LC3B)
MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. MAP1LC3B is one of the light chain subunits and can associate with either MAP1A or MAP1B. It is a Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). LC3B plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.
Product Specifications
CAS Number
9007-83-4
UniProt
Q9GZQ8
Host
Rabbit
Immunogen
A portion of amino acids 89-122 from the human protein was used as the immunogen for this LC3B antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, ICC, ELISA
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the LC3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This LC3B antibody is available for research use only.
Documents
Frequently Asked Questions
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