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NKX2.5 Antibody

This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P52952

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 2-5 from the human protein was used as the immunogen for this NKX2.5 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NKX2.5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NKX2.5 antibody is available for research use only.

Storage Conditions

Aliquot the NKX2.5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the NKX2.5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

NKX2.5 antibody western blot analysis in mouse liver tissue lysate. Predicted molecular weight ~35kDa, routinely observed at 35~45kDa.

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