DR6 Antibody (Death Receptor 6)
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
O75509
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DR6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DR6 antibody is available for research use only.
Storage Conditions
Aliquot the DR6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the DR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Rat
Image Legend
DR6 antibody western blot analysis in A549 lysate.
Documents
Frequently Asked Questions
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