BMP3 Antibody
The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, IHC (Paraffin) : 1:50-1:100
UniProt
P12645
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 8-36 from the human protein was used as the immunogen for this BMP3 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC, ELISA
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the BMP3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This BMP3 antibody is available for research use only.
Storage Conditions
Aliquot the BMP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the BMP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
Western blot analysis of BMP3 antibody and 293 lysate. Predicted molecular weight ~55 kDa.
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