RHO Antibody / Rhodopsin
Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form, which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
P08100
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 310-339 from human Rhodopsin was used as the immunogen for this RHO antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RHO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RHO antibody is available for research use only.
Storage Conditions
Aliquot the RHO antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the RHO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Primate
Image Legend
RHO antibody western blot analysis in MDA-MB453 lysate. Predicted molecular weight: 40 kDa.
Documents
Frequently Asked Questions
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