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IQGAP1 Antibody

This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000

UniProt

P46940

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 256-285 from the human protein was used as the immunogen for this IQGAP1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, ELISA

Purity

Antigen affinity

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the IQGAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This IQGAP1 antibody is available for research use only.

Storage Conditions

Aliquot the IQGAP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

Titration of the IQGAP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IQGAP1 antibody western blot analysis in T47D lysate. Predicted molecular weight ~189 kDa.

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