PCSK4 Antibody
Proprotein convertases, including PCSK4, are calcium-dependent serine proteases related to bacterial subtilisins and to yeast kexin. These enzymes process precursor proteins to their active forms by selective cleavage of the polypeptide at sites following paired basic amino acids. In mammals, this family comprises PC1 (MIM 162150), PC2 (MIM 162151), PC4, PC5 (MIM 600488), furin (FUR; MIM 136950), and PACE4 (MIM 167405) . Substrates for these enzymes range from prohormones to precursors for growth factors to cell surface receptors and viral surface glycoproteins (Cao et al., 2001 [PubMed 11776387]) .[supplied by OMIM].
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q6UW60
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 168-196 from the human protein was used as the immunogen for this PCSK4 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS pH 7.4 with 0.09% sodium azide
Reconstitution
Aliquot the PCSK4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PCSK4 antibody is available for research use only.
Storage Conditions
Aliquot the PCSK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the PCSK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
PCSK4 antibody western blot analysis in SK-BR-3 lysate.
Frequently Asked Questions
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