TGFBI Antibody
Transforming growth factor-beta-induced protein ig-h3 is a RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000, Flow Cytometry: 1:10-1:50
UniProt
Q15582
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 106-135 from the human protein was used as the immunogen for this TGFBI antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TGFBI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TGFBI antibody is available for research use only.
Storage Conditions
Aliquot the TGFBI antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the TGFBI antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Prediction Reactivity
Mouse, Pig, Rabbit
Image Legend
Western blot analysis of TGFBI antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the TGFBI gene.
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