WNT6 Antibody
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:1000
UniProt
Q9Y6F9
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 173-201 from the human protein was used as the immunogen for this WNT6 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, ELISA
Purity
Antigen affinity
Format
Antigen affinity purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the WNT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This WNT6 antibody is available for research use only.
Storage Conditions
Aliquot the WNT6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Titration of the WNT6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Image Legend
WNT6 antibody western blot analysis in HepG2 lysate
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